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酒精性肝病研究进展
作者:李玥  杨松 
单位:首都医科大学附属北京地坛医院 
关键词:酒精性肝病 酒精性肝炎 铁死亡 阿坎酸 肝移植 
分类号:
出版年,卷(期):页码:2022,14(3):1-4
摘要:
摘要:酒精性肝病(alcoholic liver disease,ALD)是危害我国人民健康的主要肝脏疾 病之一。党的十八大以来,我国肝病领域研究人员与全球同道一起围绕ALD进行深入 研究并取得重要进展。在ALD发病机制领域,进一步阐明了基因多态性、肠道微生态 和铁死亡在酒精性肝病中的重要作用。在ALD诊疗领域,针对ALD维持戒酒、重症酒 精性肝炎药物治疗及ALD肝移植等方面工作不断突破。但我国ALD防控形势依旧严 峻,仍需针对ALD的发病机制与诊疗进行深入研究,以期切实改善ALD患者预后,进 一步降低ALD的社会负担。
Abstract: Alcoholic liver disease (ALD) is one of the major liver diseases endangering the health of Chinese. Since the 18th National Congress of the Communist Party of China, Chinese and global researchers in hepatology conducted comprehensive research and made significant progress in ALD. In area of pathogenesis, studies further clarify the role of gene polymorphism, intestinal microecology and ferroptosis in pathogenesis of ALD. As for management of ALD, continuous breakthroughs have been made in areas of abstinence maintaining, treatment for severe alcoholic hepatitis, and liver transplantation for ALD. Yet, the situation of prevention and control of ALD in China is still a challenge. Comprehensive researches in pathogenesis and management of ALD are needed to effectively improve the prognosis of ALD patients and further reduce the social burden of ALD.
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